AACR Accepted Poster Abstracts

*Red highlighted posters will include a pre-recorded 5 minute presentation and will be presented on Day One

Poster Title: NGS-Based Murine Pan-Cancer Gene Expression Panel reveals high resolution for Immuno-Oncology and Tumor Microenvironment Studies

Author block: Jia Xue, Xiaobo Chen, Henry Q. Li, Sheng Guo

Session: Tumor biology - Gene expression and the TME

Poster Title: Characterization of a panel of orthotopic bioluminescent patient-derived models for drug discovery

Author block: Jessie Wang, Jun Zhou, Ling Chen, Rongyun Zhou, Henry Q.X. Li, Xiaoxi Xu, Davy X. Ouyang

Session: Tumour biology - PDX models

Poster Title: Establishment and Characterization of a series of Lymphoma PDX models to represent varied clinical behaviors and treatment responses

Author block: Jessie Wang, Yanrui Song, Jitai Zheng, Guiqing Wu, Likun Zhang, Henry Q.X. Li, Davy X. Ouyang

Session: Tumour biology - PDX models

Poster Title: Tracing T cell activation cytokines in reporter models by bioluminescence imaging

Author block: Ying Jin1, Kaixia Lian1, Fengge Li1, Ruilin Sun2, Annie X. An1, Henry Q.X. Li1, Davy X. Ouyang1

Session: Immunology - Novel Animal models

Poster Title: Characterization of a humanized TLR8 mouse model and its application in Immuno-Oncology drug development

Author block: Hongjuan Zhang1, Ruilin Sun2, Annie X. An1, Henry Q.X. Li1, Davy X. Ouyang1

Session: Clinical Research - Inflammation, Immunity and cancer

Poster Title: Establishment and Characterization of a Series of Murine Cancer Homograft Models Derived from Induced Cancer Stem Cells (iCSCs)

Author block: Jessie Wang, Likun Zhang, Annie X An, Henry Q.X. Li, Davy X. Ouyang

Session: Tumor biology - Mouse models of Human Cancer

Poster Title: The impact of drinking water pH on anti-PD1 efficacy in the experimental mice

Author block: Ying Jin, Guangmao Mu, Fengge Li, Huajun Zhou, Annie X. An, Bonnie Chen, Henry Q.X. Li, Davy X. Ouyang

Session: Tumor biology - Mouse models of Human Cancer

Poster Title: In vitro Characterization of Antibodies Targeting SIRPα–CD47 Phagocytosis Checkpoint using Tumor-associated Macrophages from HuGEMM mice

 

Author block: Xuefei Yan, Hongjuan Zhang, Yi Liu, Yahong Zhang, Lei Zheng, Mingfa Zang, Annie An, Kevin Xu, Davy Xuesong Ouyang, Henry Li and Yujun Huang

Session: Clinical Research - Immune checkpoints

Poster Title: Anti-human TNFR2 antagonist can induce T cell proliferation and restore T cell balance to promote tumor killing in TNFR2 HuGEMM engrafted with MC38/OVA tumor cells

Author block: Daniel X. He, Lei Zheng, Tianyi Qian, Annie X. An, Henry Q.X. Li, Davy X. Ouyang

Session: Immunology - Novel Animal models

Poster Title: In vitro and In vivo establishment of CD3EDG HuGEMM Platform for CD3 BiTE Evaluation

Author block: Daniel X. He1, Lei Zheng1, Ruilin Sun2, Annie X. An1, Henry Q.X. Li1, Davy X. Ouyang1

Session: Immunology - Novel Animal models

Poster Title: Evaluating variation of drug efficacy endpoints in syngeneic mouse model (CT26) under ICB treatment

Author block: Binchen Mao1, Sheng Guo1, Davy Ouyang1, Henry Q. Li1

Session: Bioinformatics, convergence science & systems biology - Statistical methods

Poster Title: Comparison of Illumina Novaseq 6000 and MGISEQ2000 in profiling xenograft models

Author block: Wubin Qian, Xiaobo Chen, Henry Q. Li and Sheng Guo

Session: Bioinformatics, convergence science & systems biology - Sequence Analysis

Poster Title: An ultra-accurate NGS assay revealed great variation of mouse ratios in xenograft tumors by mouse strain and cancer type

Author block: Wubin Qian, Sheng Guo

Session: Tumour biology - PDX models

Poster Title: Detection of Structural Variation and Analysis on HuKemia models by Using BioNano Optical Mapping

Author block: Xiaobo Chen1, Huan Tian1, Wubin Qian1, Henry Q. Li2 and Sheng Guo1

Session: Molecular & Cellular Biology/Genetics - Genomic profiling of tumours