8:30 am Login & Join our coffee chat room

9:00 am Chair’s Welcome

  • Rajendra Kumari Global Head of Scientific Communication, Crown Bioscience

Immuno-Oncology Preclinical Study Advancements

9:10 am Understanding the Mechanistic Actions & Development of IL-15Rβγ Agonist

Synopsis

  • Addressing the challenges in preclinical testing of molecules activating immune system
  • Limitations of models and how to define the right strategy and assumptions in preclinical studies
  • Lessons learned and future testing approaches

9:40 am Advancing Immuno-Oncology Therapies: What are the Next Generation Syngeneic Models?

  • Ludovic Bourre Senior Director, Scientific Engagement, Crown Bioscience

Synopsis

• Which models/approaches to understand the mechanism of action?
• Immune-related adverse event (irAE) assessment of therapeutic antibodies with target specific KI models

10:10 am Designing the Next IO Model to Enhance Translatability

Synopsis

• How to mimic human physiology and immune response from the mouse model?
• Boosting our clinical confidence by testing efficacy, dosing and safety in your IO models
• Challenges and opportunities through new technologies

10:40 am Roundtable Discussion: What Preclinical Models Provide a Platform to Assess Immunotherapy Toxicology?

  • Georgina Cornish Associate Principle Scientist, Cell Therapy Safety, AstraZeneca
  • Ludovic Bourre Senior Director, Scientific Engagement, Crown Bioscience

Synopsis

Take advantage of this interactive session to join our expert speakers in the roundtable to ask your burning questions, share your recent preclinical success and hear how your peers have tackle similar problems to get inspirations!

11:15 am Poster Session

Synopsis

We are excited about the unreleased data which will be revealed during the Poster Session. Below is only a sneak peek of what is available. Register to join this exclusive meeting to be the first to gain access to these poster.

On the day, you will also get the opportunity to ask our poster presenters your burning questions about their research publications!

12:00 pm Chair’s Closing Remarks & End of Day 1

  • Rajendra Kumari Global Head of Scientific Communication, Crown Bioscience